A striking periodicity of the cis/trans isomerization of proline imide bonds in cyclic disulfide-bridged peptides.
A striking periodicity of the cis/trans isomerization of proline imide bonds in cyclic disulfide-bridged peptides.
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DOI：
10.1002/anie.200503470
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发表时间：
2006-03
影响因子：
--
通讯作者：
T. Shi;Stephen M. Spain;D. Rabenstein
中科院分区：
文献类型：
--
作者：
T. Shi;Stephen M. Spain;D. Rabenstein
大于7R和7O的缩氨酸由于在水中的溶解度低，没有被研究。[b]采用快速原子轰击法（FAB-MS）或基质辅助激光解吸/电离质谱法（MALDI-MS）测量。[c]磁转移核磁共振实验中顺式和反式异构体的共振对。[d]肽30在水溶液中异构成未被表征的反应混合物；30也非常吸湿。[e]资料来自参考文献。[f]没有合适的顺式/反式共振对用于反转磁化转移实验。
7O 720.3 (720) Acetyl CH3 [a] Peptides larger than 7R and 7O were not studied because of low solubility in water.[b] Measured either by fast atom bombardment (FAB-MS) or by matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS).[c] The pair of resonances for the cis and trans isomers used in magnetization-transfer NMR experiments.[d] Peptide 3O isomerizes in aqueous solution to a reaction mixture that was not characterized; 3O also is extremely hygroscopic.[e] Data from ref.[8].[f] No suitable cis/trans pair of resonances could be found for the inversion magnetization-transfer experiments.