Visual Perception Disturbances in Schizophrenia: A Unified Model
Visual Perception Disturbances in Schizophrenia: A Unified Model
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DOI：
10.1007/978-3-319-30596-7_4
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发表时间：
2016-01-01
期刊：
影响因子：
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通讯作者：
Silverstein, Steven M.
中科院分区：
文献类型：
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作者：
Silverstein, Steven M.
本章的目的是证明精神分裂症视觉加工异常的研究为精神分裂症的病因、发展、病理生理学和病程提供了一个统一的视角。本章共分六节。首先，我简要概述了在精神分裂症中研究视力的重要性和前景。在第二部分中，我提供了患者所报告的视觉多方面的改变的视觉体验的例子。第三部分回顾了与精神分裂症相关的最显著的视觉任务缺陷的研究和争议，包括它们的心理生理学和神经生物学方面。在第四章中，我介绍了语境调节的概念，并讨论了这一功能的过度和减少，以及刺激敏感度的总体水平的变化，是如何解释与精神分裂症相关的许多视觉任务缺陷的。在了解了所有这些证据后，我简短地回到了精神分裂症患者的世界是什么样子的问题上，以及这种情况可能会在疾病阶段发生什么变化。文章最后对视觉和精神分裂症领域的未来研究方向进行了展望。
The purpose of this chapter is to demonstrate that the study of visual processing abnormalities in schizophrenia offers a unifying perspective on the etiology, development, pathophysiology, and course of the disorder. This chapter contains six sections. In the first, I provide a brief overview of the importance and promise of studying vision in schizophrenia. In the second, I provide examples of altered visual experience, in multiple aspects of vision, as reported by patients. The third reviews research and controversies related to the most prominent schizophrenia-related visual task deficits, including their psychophysiological and neurobiological aspects. In the fourth, I introduce the construct of contextual modulation and discuss how excesses and reductions in components of this function, in addition to changes in overall level of stimulus sensitivity, can account for many of the visual task deficits associated with schizophrenia. Informed by all of this evidence, I then briefly return to the issue of what the world looks and feels like for people with schizophrenia, and how this may change across illness phases. The paper concludes with a section on future directions for research in the area of vision and schizophrenia.