Functional remediation in bipolar disorder: 1-year follow-up of neurocognitive and functional outcome
Functional remediation in bipolar disorder: 1-year follow-up of neurocognitive and functional outcome
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DOI：
10.1192/bjp.bp.114.162123
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发表时间：
2016-01-01
影响因子：
10.5
通讯作者：
Martinez-Aran, A.
中科院分区：
文献类型：
--
作者：
Bonnin, C. M.;Torrent, C.;Martinez-Aran, A.
BackgroundFew randomized clinical trials have examined efficacy of an intervention aimed at improving psychosocial functioning in bipolar disorder.AimsTo examined changes in psychosocial functioning in a group that has been enrolled in a functional remediation programme 1 year after baseline.MethodThis is a multicentre，randomized，rater-masked clinical trial comparing three patient groups：功能性补救、心理教育和治疗，1年随访。主要结果是通过功能评估简短测试（FAST）测量的心理社会功能的变化。使用重复测量ANOVA（试验注册NCT 01370668）检查组x时间对整体心理社会功能的影响。2，P=0.049）.ConclusionsImprovement in psychosocial functionality is maintained after 1 year follow-up in patients with bipolar disorder receiving functional remediation.Copyright and usage（C）The皇家精神科医师学院2016.
BackgroundFew randomised clinical trials have examined the efficacy of an intervention aimed at improving psychosocial functioning in bipolar disorder.AimsTo examine changes in psychosocial functioning in a group that has been enrolled in a functional remediation programme 1 year after baseline.MethodThis was a multicentre, randomised, rater-masked clinical trial comparing three patient groups: functional remediation, psychoeducation and treatment as usual over 1-year follow-up. The primary outcome was change in psychosocial functioning measured by means of the Functioning Assessment Short Test (FAST). Group x time effects for overall psychosocial functioning were examined using repeated-measures ANOVA (trial registration NCT01370668).ResultsThere was a significant group x time interaction for overall psychosocial functioning, favouring patients in the functional remediation group (F=3.071, d.f.=2, P=0.049).ConclusionsImprovement in psychosocial functioning is maintained after 1-year follow-up in patients with bipolar disorder receiving functional remediation.Copyright and usage(C) The Royal College of Psychiatrists 2016.