A tomato-rich diet is related to depressive symptoms among an elderly population aged 70 years and over: A population-based, cross-sectional analysis
A tomato-rich diet is related to depressive symptoms among an elderly population aged 70 years and over: A population-based, cross-sectional analysis
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DOI：
10.1016/j.jad.2012.04.040
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发表时间：
2013-01-10
影响因子：
6.6
通讯作者：
Nagatomi, Ryoichi
中科院分区：
文献类型：
--
作者：
Niu, Kaijun;Guo, Hui;Nagatomi, Ryoichi
背景：氧化应激增强或抗氧化防御缺陷与抑郁症状的发病机制有关。番茄红素是类胡萝卜素中最强的抗氧化剂。这项研究的目的是调查不同的蔬菜，包括番茄/番茄制品(番茄红素的主要来源)与以社区为基础的老年人口中抑郁症状的关系。方法：我们分析了一项横断面调查，其中包括986名70岁及以上的日本社区居民。采用有效的自填式饮食史问卷评估膳食摄入量，以30项老年抑郁量表评定抑郁症状，以11项(轻度和重度)和14项(重度)或使用抗抑郁药物为分界点。结果：轻度、重度和重度抑郁症状的发生率分别为34.9%和20.2%。在调整了潜在的混杂因素后，通过增加番茄/番茄制品的水平而出现轻度和重度抑郁症状的优势比分别为1.00、0.54和0.48(p为趋势
Background: Enhanced oxidative stress or defective anti-oxidant defenses are related to the pathogenesis of depressive symptoms. Lycopene is the most powerful antioxidant amongst the carotenoids. The aim of this study was to investigate the relationship between different vegetables, including tomatoes/tomato products (a major source of lycopene), and depressive symptoms in a community-based elderly population.Methods: We analyzed a cross-sectional survey including 986 community-dwelling elderly Japanese individuals aged 70 years and older. Dietary intake was assessed using a valid self-administered diet-history questionnaire, and depressive symptoms were evaluated using the 30-item Geriatric Depression Scale with 2 cut-off points: 11 (mild and severe) and 14 (severe) or use of anti-depressive agents.Results: The prevalence of mild and severe and severe depressive symptoms was 34.9% and 20.2%, respectively. After adjustments for potentially confounding factors, the odds ratios of having mild and severe depressive symptoms by increasing levels of tomatoes/tomato products were 1.00, 0.54, and 0.48 (p for trend