Determinants of adherence to non-occupational post HIV exposure prophylaxis
Determinants of adherence to non-occupational post HIV exposure prophylaxis
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DOI：
10.1097/01.aids.0000199832.10478.83
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发表时间：
2006-01-09
期刊：
影响因子：
3.8
通讯作者：
Meyohas, MC
中科院分区：
文献类型：
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作者：
Lacombe, K;Daguenel-Nguyen, A;Meyohas, MC
我们对140名在非职业性暴露后到医院寻求建议的患者进行了研究。109名患者完成了为期28天的预防性抗逆转录病毒治疗。未观察到HIV污染。与次优依从性相关的因素是非洲种族[比值比（OR）13.3，2.02-87.54]和口交（OR 8.35，1.66-41.99）。可以通过消除社会和心理障碍来提高预防性抗逆转录病毒治疗的依从性。
We conducted a study on 140 patients who sought advice at hospital after a non-occupational exposure. The full 28-day course of prophylactic antiretroviral therapy was completed by 109 patients. No HIV contamination was observed. Factors associated with suboptimal adherence were African ethnicity [odds ratio (OR) 13.3, 2.02-87.54] and oral sexual intercourse (OR 8.35, 1.66-41.99). Compliance with prophylactic antiretroviral therapy can be increased by addressing social and psychological barriers to adherence.