Impact of diabetes on cardiac structure and function - The strong heart study
Impact of diabetes on cardiac structure and function - The strong heart study
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DOI：
10.1161/01.cir.101.19.2271
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发表时间：
2000-05-16
期刊：
影响因子：
37.8
通讯作者：
Howard, BV
中科院分区：
文献类型：
--
作者：
Devereux, RB;Roman, MJ;Howard, BV
背景-糖尿病(DM)是否独立于体重指数(BMI)和血压的增加而对左心室(LV)结构和功能产生不利影响仍存在争议。方法和结果-在美国印第安人心血管疾病研究中，超声心动图被用于比较1810名DM参与者和944名糖耐量正常的参与者的LV测量。糖尿病患者年龄较大(平均年龄分别为60岁和59岁)，BMI(32.4 kg/m~2比28.9 kg/m(2))和收缩压(133比124 mm Hg)更高，而且更有可能是女性，正在接受降压治疗，并居住在亚利桑那州(均P
Background-Whether diabetes mellitus (DM) adversely affects left ventricular (LV) structure and function independently of increases in body mass index (BMI) and blood pressure is controversial.Methods and Results-Echocardiography was used in the Strong Heart Study, a study of cardiovascular disease in American Indians, to compare LV measurements between 1810 participants with DM and 944 with normal glucose tolerance. Participants with DM were older (mean age, 60 versus 59 years), had higher BMI (32.4 versus 28.9 kg/m(2)) and systolic blood pressure (133 versus 124 mm Hg), and were more likely to be female, to be on antihypertensive treatment, and to live in Arizona (all P