A subspace approach to high-resolution spectroscopic imaging.
A subspace approach to high-resolution spectroscopic imaging.
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DOI:
10.1002/mrm.25168
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发表时间:
2014-04
影响因子:
3.3
通讯作者:
Liang, Zhi-Pei
中科院分区:
文献类型:
--
作者:
Lam, Fan;Liang, Zhi-Pei
关键词:
To accelerate spectroscopic imaging using sparse sampling of (k, t)-space and subspace (or low-rank) modeling to enable high-resolution metabolic imaging with good signal-to-noise ratio (SNR). The proposed method, called SPICE (SPectroscopic Imaging by exploiting spatiospectral CorrElation), exploits a unique property known as partial separability of spectroscopic signals. This property indicates that high-dimensional spectroscopic signals reside in a very low-dimensional subspace and enables special data acquisition and image reconstruction strategies to be used to obtain high-resolution spatiospectral distributions with good SNR. More specifically, a hybrid CSI/EPSI pulse sequence is proposed for sparse sampling of (k, t)-space, and a low-rank model-based algorithm is proposed for subspace estimation and image reconstruction from sparse data with the capability to incorporate prior information and field inhomogeneity correction. The performance of SPICE has been evaluated using both computer simulations and phantom studies, which produced very encouraging results. For 2D spectroscopic imaging experiments on a metabolite phantom, a factor of 10 acceleration was achieved with a minimal loss in SNR compared to the long CSI experiments and with a significant gain in SNR compared to the accelerated EPSI experiments. SPICE is able to significantly accelerate spectroscopic imaging experiments, making high-resolution metabolic imaging possible.
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