Effects of Successive Air and Trimix Dives on Human Cardiovascular Function
Effects of Successive Air and Trimix Dives on Human Cardiovascular Function
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DOI：
10.1249/mss.0b013e3181aa04cc
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发表时间：
2009-12-01
期刊：
影响因子：
--
通讯作者：
Dujic, Zeljko
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文献类型：
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作者：
Marinovic, Jasna;Ljubkovic, Marko;Dujic, Zeljko
马林诺维奇，J. M.柳布科维奇，A. OBAD， D. BAKOVIC， T. BRESKOVIC，和Z. DUJIC。医学科学。体育Exerc。， Vol. 41, No. 12, pp. 2207-2212, 2009。简介：在潜水员人群中，三混合气（氧气、氦气和氮气的混合物）的使用显著增加。然而，表明在最常见深度的trimix潜水如何影响心血管功能的数据很少。本研究的目的是调查三自由度潜水对心血管的影响，并将其与空气潜水进行比较，并确定连续几天的重复潜水是否会影响其程度。方法：9名专业潜水员连续4天下潜，下潜深度逐步增加，最大下潜深度55 m。潜水员在第一次潜水时使用空气，第二次潜水时使用氮气25，第三次和第四次潜水时使用混合气体20/30。每次潜水前后均行超声心动图检查。结果：每次潜水后，左心室射血分数和分数缩短明显降低，收缩末期体积增加，但舒张末期体积没有变化，表明心脏左侧收缩功能下降。评估肺动脉加速时间与右心室射血时间之比（用作肺动脉压（PAP）的指标）显示，在所有潜水后，PAP都有所增加。没有发现多次潜水的生理相关累积效应或适应的迹象。结论：目前的研究表明，混合潜水对心血管的影响与压缩空气潜水没有什么不同。然而，这表明即使是一个非常安全和保守的混合型潜水也会对心血管产生显著影响。
MARINOVIC, J., M. LYUBKOVIC, A. OBAD, D. BAKOVIC, T. BRESKOVIC, and Z. DUJIC. Med. Sci. Sports Exerc., Vol. 41, No. 12, pp. 2207-2212, 2009. Introduction: The use of trimix (a mixture of oxygen, helium, and nitrogen) has significantly increased among the diver population. However, data indicating how trimix dives at most common depths affect the cardiovascular function are sparse. The purpose of this study was to investigate the cardiovascular effects of trimix dives and compare them with air dives and to determine whether the repetition of dives in successive days affects their extent. Methods: Nine professional divers performed four dives in consecutive days where the dive depth was progressively increased to the maximum of 55 m. Divers used air in the first dive, nitrox 25 in the second, and trimix 20/30 in the third and fourth dives. Echocardiography was performed before and after each dive. Results: After each dive, a significantly decreased left ventricular ejection fraction and fractional shortening and an increased end-systolic volume without a change in end-diastolic volume were found, indicating a depressed systolic function of the left side of the heart. Assessment of the ratio between pulmonary artery acceleration time and right ventricular ejection time (used as an indicator of pulmonary artery pressure (PAP)) revealed an increase in PAP after all the dives. No physiologically relevant cumulative effects of the multiple dives or signs of acclimatization were found. Conclusions: The current study shows that the cardiovascular effects of trimix dives do not differ from those of the dives with compressed air. However, it suggests that even a very safe and conservative trimix diving profile exerts significant cardiovascular effects.