Purification of an extracellular signaling molecule involved in production of aerial mycelium by Streptomyces coelicolor

Purification of an extracellular signaling molecule involved in production of aerial mycelium by Streptomyces coelicolor
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DOI:
10.1128/jb.180.5.1334-1337.1998
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发表时间:
1998-03-01
影响因子:
3.2
通讯作者:
Losick, R
Losick, R
中科院分区:
生物学3区
文献类型:
--
作者:
Nodwell, JR;Losick, R

文献摘要

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We have extensively purified a factor from conditioned medium that restores aerial mycelium formation to a mutant of Streptomyces coelicolor that is defective in morphological differentiation. Response to this factor is shown to depend on the presence of the BIdK oligopeptide import system. We suggest that this substance acts at the first step in a putative cascade of developmental regulatory signals.