Simulation of measured activation sequence in the human heart.
Simulation of measured activation sequence in the human heart.
复制标题
模拟测量的人类心脏激活序列。
DOI：
10.1016/0002-8703(73)90497-3
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发表时间：
1973
影响因子：
4.8
通讯作者：
Ronald H. Selvester
中科院分区：
文献类型：
--
作者：
Joseph C. Solomon;Ronald H. Selvester
模拟人体心脏产生的电场，它是基于物理原理，并包含所有的一阶影响，提供了一个模型来执行实验和收集数据的可能性，否则将难以获得直接从人类受试者。我们的努力是针对开发这样一个模拟程序，这份报告涉及的计算机模型，以模拟在心脏去极化波前。从模拟程序中获得了心脏几何形状的心室去极化路径，并且结果的分析将限于从离体人类心脏报告的壁内兴奋模式与模拟程序给出的那些兴奋模式之间的定性比较。很明显，在模型的介绍和获得的结果，有一个更基本的研究量化浦肯野网络和传导束插入的属性和结构是非常必要的。
S imulation of the electric field produced by the human heart, which is based on physical principles and contains all of the first order influences, offers the possibility of a model to perform experiments and collect data that would otherwise be difficult to obtain directly from human subjects. Our efforts are directed at developing such a simulation program, and this report deals with the computer model to simulate the depolarization wavefront in the heart. A pathway of ventricular depolarization for a heart geometry was obtained from the simulation program, and the analysis of the results will be confined to a qualitative comparison between intramural excitation patterns reported from isolated human hearts’ and those excitation patterns given by the simulation program. It is clear in the presentation of the model and the results obtained that there is a great need for more basic research into quantifying the properties and structure of the Purkinje network and the conduction bundle insertion.