Comparison of Copper(II) Oxide Nanostructures with Different Morphologies for Nonenzymatic Glucose Sensing
Comparison of Copper(II) Oxide Nanostructures with Different Morphologies for Nonenzymatic Glucose Sensing
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DOI：
10.1021/acsanm.2c05433
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发表时间：
2023-01-12
影响因子：
5.9
通讯作者：
Stein, Andreas
中科院分区：
文献类型：
--
作者：
Fan, Baoyue;Spindler, Brian D.;Stein, Andreas
研究了用于非酶葡萄糖传感器的具有三种不同形态（球形、片状和针状）的氧化铜（II）颗粒所实现的葡萄糖敏感性。 CuO 纳米颗粒的形貌由不同的合成参数控制，包括 Cu(II) 离子沉淀剂的变化、pH 值、煅烧方案以及表面活性剂和过氧化氢的添加。研究了氧化铜 (II) 颗粒形态在非酶葡萄糖传感中的作用。研究了电催化过程中材料的几种形态特性的主要驱动因素。我们研究了氧化铜的暴露晶面、比表面积、孔体积和晶粒尺寸对葡萄糖敏感性的影响。该研究表明，葡萄糖传感中的电催化性能主要与氧化铜纳米粒子的晶粒尺寸和由此引入的电容相关。针状 CuO 纳米粒子在该应用中呈现出最佳的形态，对葡萄糖具有良好的敏感性（2.05 mA 中心点 mM-1 中心点 cm-2）、0.05-5 mM 葡萄糖的线性范围以及这些材料中最好的长期稳定性。这项工作深入了解了氧化铜基材料在生物传感器中的潜在用途，以及金属氧化物基纳米粒子在传感应用中的主要影响因素。
The glucose sensitivity achieved with copper(II) oxide particles with three different morphologies (spheres, platelets, and needles) for application in nonenzymatic glucose sensors was investigated. The morphologies of CuO nanoparticles were controlled by different synthesis parameters, including changes in precipitators of Cu(II) ions, pH values, calcination protocol, and the addition of surfactant and hydrogen peroxide. The role of copper(II) oxide particle morphology in nonenzymatic glucose sensing was studied. The primary driving factor in the electrocatalytic process was investigated for several morphological properties of the material. We studied the effects of exposed crystal faces, specific surface area, pore volume, and grain size of copper oxides on glucose sensitivity. This study showed that the electrocatalytic performance in glucose sensing correlates primarily with the grain size of copper oxide nanoparticles and the capacitance introduced therefrom. The needle-shaped CuO nanoparticles presented the optimal morphology in this application, resulting in good sensitivity to glucose (2.05 mA center dot mM-1 center dot cm-2), a linear range of 0.05-5 mM glucose, and the best long-term stability among these materials. This work provides insight into the potential use of CuO-based materials in biosensors and into the major contributing factors of metal oxide-based nanoparticles in sensing applications.