Zoledronic acid for relapsed Langerhans cell histiocytosis with isolated skull bone lesion.
Zoledronic acid for relapsed Langerhans cell histiocytosis with isolated skull bone lesion.
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唑来膦酸治疗复发性朗格汉斯细胞组织细胞增多症伴孤立性颅骨病变。
DOI：
10.1111/ped.13774
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发表时间：
2019
期刊：
影响因子：
--
通讯作者：
Ito E.
中科院分区：
文献类型：
--
作者：
Kudo K;Tanaka T;Kobayashi A;Terui K;Ito E.
一个女孩的情况下，研究提出谁有一个前额肿瘤在1岁，沿着溶骨性病变，被诊断为朗格汉斯细胞组织细胞增生症（LCH）。它指出，15个月后，包括颅骨和左侧耻骨在内的多处溶骨性病变治疗后，骨质LCH复发。报告指出，病变进一步复发，并接受唑来膦酸治疗，之后她表现出改善。
A case study of a girl is presented who had a forehead tumor at 1 year of age, along with osteolytic lesion that was diagnosed as Langerhans cell histiocytosis (LCH). It notes the recurrence of osseous LCH after therapy with multiple osteolytic lesions including in skull and left pubis after 15 months. It notes further recurrence of lesions and went under treatment with zoledronic acid after which she showed improvement.