Synthesis of benzyl esters using 2-benzyloxy-1-methylpyridinium triflate.

Synthesis of benzyl esters using 2-benzyloxy-1-methylpyridinium triflate.
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使用 2-苄氧基-1-甲基吡啶鎓三氟甲磺酸酯合成苄酯。

DOI:
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发表时间:
2007
影响因子:
3.6
通讯作者:
G. Dudley
G. Dudley
中科院分区:
化学2区
文献类型:
--
作者:
J. Tummatorn;Philip A. Albiniak;G. Dudley

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三乙胺(Et 3 N)介导标题试剂(1)与羧酸之间的酯化反应。醇,酚,酰胺,和其他敏感的功能不受影响;作为促进剂和清除剂的Et 3 N的双重作用被假定。苄基酯是从底物包括氨基酸和糖衍生物获得的。
Triethylamine (Et3N) mediates esterification reactions between the title reagent (1) and carboxylic acids. Alcohols, phenols, amides, and other sensitive functionality are not affected; a dual role for Et3N as a promoter and a scavenger is postulated. Benzyl esters are obtained from substrates including amino acid and sugar derivatives.