Chemically tunable lensing of stimuli-responsive hydrogel microdomes
Chemically tunable lensing of stimuli-responsive hydrogel microdomes
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DOI：
10.1002/adma.200601969
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发表时间：
2007-11-19
影响因子：
29.4
通讯作者：
Daunert, Sylvia
中科院分区：
文献类型：
--
作者：
Ehrick, Jason D.;Stokes, Sean;Daunert, Sylvia
化学可调谐水凝胶微透镜是由基于共价结合的铰链运动结合蛋白（如钙调蛋白）和低亲和力配体（即吩噻嗪）的丙烯酰胺水凝胶开发而成。最初，蛋白质与吩噻嗪结合，在水凝胶内形成化学交联，在水凝胶内形成化学交联时释放化学交联，在较高亲和力配体氯丙嗪存在的情况下释放化学交联，导致微透镜膨胀。
Chemically tunable hydrogel microlenses have been developed from acrylamide hydrogels based on covalently bound hinge-motion binding proteins, like calmodulin, and low affinity ligands, i.e. phenothiazine. Initially the protein binds to phenothiazine forming chemical crosslinks within the hydrogel, which are released in the forming chemical crosslinks within the hydrogel, which are released in the presence of the higher affinity ligand chlorpromazine resulting in the swelling of the microlenses.