Visual Acuity Is Associated with Performance on Visual and Non-Visual Neuropsychological Tests in Multiple Sclerosis
Visual Acuity Is Associated with Performance on Visual and Non-Visual Neuropsychological Tests in Multiple Sclerosis
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DOI：
10.1080/13854046.2011.565075
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发表时间：
2011-01-01
影响因子：
3.9
通讯作者：
Bruce, Jared M.
中科院分区：
文献类型：
--
作者：
Feaster, H. Todd;Bruce, Jared M.
视力和认知问题在多发性硬化症中都很常见。先前的研究表明，近视力受损的多发性硬化症患者在视觉介导的认知测试中表现更差。因此，建议神经心理学家在评估矫正近视力较差的多发性硬化症患者时应主要依靠听觉神经心理学测试。然而，尚无研究探讨多发性硬化症患者的视力问题与非视觉神经心理学测试表现之间的关联。此外，很少有研究探讨更敏感的视力障碍测量与多发性硬化症认知困难之间的关联。本研究的目的是探讨多发性硬化症患者视力与认知之间的关系。总共 65 名 MS 患者接受了视觉和神经心理学评估。视力检查包括视力、低对比度视力（5%、2.5% 和 1.25% 照明视力表）和近视力的评估。较差的高对比度、近处和低对比度视敏度与视觉、非视觉和基于运动的神经心理学测试的较差表现显着相关。神经心理学家应该意识到，多发性硬化症患者的矫正视力不佳与所有认知和运动领域的表现不佳有关。结果表明需要进一步探索 MS 疾病进展的视力生物标志物。
Both vision and cognitive problems are commonplace in multiple sclerosis. Previous research suggests that MS patients with compromised near vision perform more poorly on visually mediated cognitive tests. Consequently it has been recommended that neuropsychologists who evaluate MS patients with poor corrected near vision should rely primarily on auditory neuropsychological tests. However, no research has examined the association between vision problems and performance on non-visual neuropsychological tests in MS. Moreover, little if any research has examined the association between more sensitive measures of vision impairment and cognitive difficulties in MS. The objective of this study was to examine the relationship between visual acuity and cognition in MS. A total of 65 MS patients were administered a visual and neuropsychological evaluation. Visual examination included an assessment of visual acuity, low-contrast visual acuity (5%, 2.5%, and 1.25% illuminated charts) and near visual acuity. Poorer high-contrast, near, and low-contrast visual acuity were significantly associated with poorer performance on visual, non-visual, and motor-based neuropsychological tests. Neuropsychologists should be aware that poor corrected vision in MS is associated with poor performance in all cognitive and motor domains. Results suggest the need for further exploration of visual acuity biomarkers of disease progression in MS.