Necrotizing enterocolitis in full-term or near-term infants: risk factors.
Necrotizing enterocolitis in full-term or near-term infants: risk factors.
复制标题
足月或近足月婴儿的坏死性小肠结肠炎：危险因素。
DOI：
--
复制
发表时间：
1997
期刊：
影响因子：
--
通讯作者：
E. Bancalari
中科院分区：
文献类型：
--
作者：
E. Martínez;N. Claure;E. Bancalari
采用回顾性病例对照研究方法，对出生体重为2,000 g的新生儿坏死性小肠结肠炎(NEC)的发病因素进行分析。24例婴儿符合明确的NEC标准。在每个病例中，接下来的2名健康新生儿作为对照。与对照组相比，NEC组胎膜延长破裂、绒毛膜羊膜炎、1分钟和5分钟Apgar评分7分、呼吸问题、先天性心脏病、低血糖和换血的发生率显著高于对照组。仅有3例NEC患儿为健康新生儿，且在NEC发生前围产期病程不明显。在先兆子痫、母亲糖尿病、母亲滥用药物、羊水粪染和红细胞增多症的发生率方面没有差异。这些结果表明，这些较成熟的婴儿中的大多数在发生NEC之前都有易感因素。
A retrospective case-control study of necrotizing enterocolitis (NEC) affecting infants weighing > 2,000 g at birth was performed to determine those factors which could contribute to the development of NEC. Twenty-four infants met the criteria of definite NEC. For each case the next 2 healthy newborns were matched as controls. When compared with the control group, NEC infants had a significantly higher frequency of prolonged rupture of membranes, chorioamnionitis, Apgar score < 7 at 1 and 5 min, respiratory problems, congenital heart disease, hypoglycemia, and exchange transfusions. Only 3 infants with NEC were healthy newborns with an unremarkable perinatal course before NEC. There were no differences in the frequency of preeclampsia, maternal diabetes, maternal drug abuse, meconium-stained amniotic fluid and polycythemia. These results indicate that most of these more mature infants have a predisposing factor before developing NEC.