A Chemical Approach to Optimizing Bioactive Glass Dental Composites
A Chemical Approach to Optimizing Bioactive Glass Dental Composites
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DOI：
10.1177/0022034518809086
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发表时间：
2019-02-01
影响因子：
7.6
通讯作者：
Koley, D.
中科院分区：
文献类型：
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作者：
Aponso, S.;Ummadi, J. G.;Koley, D.
牙科复合材料周围的化学微环境在控制这些特殊表面上生长的细菌方面起着至关重要的作用。在这项研究中，我们报告了一种基于扫描电化学显微镜（SECM）的分析技术，设计和优化金属离子释放生物活性玻璃（BAG）复合材料，这表明生物膜生长显着减少。SECM允许在不接触衬底的情况下定位探针，同时在衬底上方的三维空间中映射化学参数。使用SECM和固态H+和Ca2+离子选择性微探针，我们确定了不同复合材料释放的局部Ca2+浓度为10至224 μ M，BAG颗粒尺寸为
The chemical microenvironment surrounding dental composites plays a crucial role in controlling the bacteria grown on these specialized surfaces. In this study, we report a scanning electrochemical microscopy (SECM)-based analytic technique to design and optimize metal ion-releasing bioactive glass (BAG) composites, which showed a significant reduction in biofilm growth. SECM allows positioning of the probe without touching the substrate while mapping the chemical parameters in 3-dimensional space above the substrate. Using SECM and a solid-state H+ and Ca2+ ion-selective microprobe, we determined that the local Ca2+ concentration released by different composites was 10 to 224 mu M for a BAG particle size of