Effectiveness of ginger for prevention of nausea and vomiting after gynecological laparoscopy.
Effectiveness of ginger for prevention of nausea and vomiting after gynecological laparoscopy.
复制标题
生姜预防妇科腹腔镜术后恶心呕吐的功效。
DOI：
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发表时间：
2006
影响因子：
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通讯作者：
Budsaba Wiriyasirivej
中科院分区：
文献类型：
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作者：
S. Apariman;S. Ratchanon;Budsaba Wiriyasirivej
目的
探讨生姜预防妇科腹腔镜术后恶心呕吐的效果。
材料和方法
从2005年7月至2005年10月，60例在曼谷大都会行政医学院或Vajira医院因非癌症妇科疾病接受腹腔镜手术的住院患者被随机分为A组（n = 30）或B组（n = 30）。A组接受3粒生姜胶囊（1粒胶囊含0.5 g姜粉），而B组接受3粒安慰剂胶囊。两组均于术前1小时服药。术后2 h和6 h用视觉疼痛评分（VAS）评估恶心和呕吐情况，并观察是否存在呕吐。
结果
A组术后2小时的中位VAS与B组无显著差异，中位VAS分别为0（范围，0-5.4）和0.15（范围，0-10）（95% CI为-2.59至0.90，p = 0.142）。术后6小时，A组的中位VAS显著低于B组，分别为0.55（范围，0-7.4）和2.80（范围，0-10）（95% CI为-3.61至-0.73，p = 0.015）。两组间2小时呕吐的发生率无差异，A组为10%，B组为20%（95% CI为-28%至8%，p = 0.278）。6小时时，A组23.3%的患者发生呕吐，而B组为46.7%（95% CI为-47%至1%，p = 0.058）。
结论
生姜对预防妇科腹腔镜术后6小时恶心和呕吐有一定的预防作用。
OBJECTIVE
To study the effectiveness of ginger for prevention of nausea and vomiting after gynecological laparoscopy.
MATERIAL AND METHOD
From July 2005 to October 2005, 60 inpatients who underwent laparoscopic operations for non-cancer gynecologic conditions at Bangkok Metropolitan Administration Medical College or Vajira Hospital were randomized into Group A (n = 30) or Group B (n = 30). Group A received 3 capsules of ginger (1 capsule contained 0.5 g of ginger powder) while Group B received 3 capsules of placebo. Both groups received their medicine 1 hour prior the operation. Nausea and vomiting were assessed with the Visual Analogue Scores (VAS) and presence of vomiting at 2 and 6 hours after the operation.
RESULTS
Median VAS at 2 hours post operation of Group A was not significantly different from that of Group B with the median of 0 (range, 0-5.4) and 0.15 (range, 0-10) respectively (95% CI from -2.59 to 0.90 and p = 0.142). At 6 hours post operation, the median VAS of Group A was significantly lower than group B, 0.55 (range, 0-7.4) versus 2.80 (range, 0-10) (95% CI from -3.61 to -0.73 and p = 0.015). Presence of vomiting at 2 hours was not different between the two groups, 10% in Group A and 20% in Group B (95% CI from -28% to 8% and p = 0.278). At 6 hours, 23.3% of group A had an episode of vomiting compared to 46.7% of group B (95% CI from -47% to 1% and p = 0.058).
CONCLUSION
Ginger has shown efficacy for prevention of nausea and borderline significance to prevention vomiting after gynecological laparoscopy at 6 hour post operation.