INFLUENCES OF SUGGESTION ON AIRWAY REACTIVITY IN ASTHMATIC SUBJECTS
INFLUENCES OF SUGGESTION ON AIRWAY REACTIVITY IN ASTHMATIC SUBJECTS
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DOI：
10.1097/00006842-196811000-00002
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发表时间：
1968-01-01
影响因子：
3.3
通讯作者：
MCFADDEN, ER
中科院分区：
文献类型：
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作者：
LUPARELLO, T;LYONS, HA;MCFADDEN, ER
在可以准确、快速和可重复地测量呼吸道阻力(Ra)的环境中，评估了暗示对支气管运动张力的影响。研究对象包括哮喘、肺气肿和限制性肺病，以及正常受试者。所有受试者都被引导相信他们吸入的刺激物或过敏原会导致支气管收缩。在所有情况下使用的实际物质都是雾化的生理盐水溶液。40名哮喘患者中有19名对实验情况有反应，Ra显著增加。12名哮喘受试者出现了全面的支气管痉挛发作，并用生理盐水安慰剂逆转了这一症状。40名非哮喘对照受试者无反应。
The effect of suggestion on bronchomotor tone was evaluated in a setting in which accurate, rapid, and reproducible measurements of airway resistance (Ra) could be made. Subjects with asthma, emphysema, and restrictive lung disease, as well as normal subjects, were studied. All subjects were led to believe that they were inhaling irritants or allergens which cause bronchoconstriction. The actual substance used in all instances was nebulized physiologic saline solution. Nineteen of 40 asthmatics reacted to the experimental situation with a significant increase in Ra. Twelve of the asthmatic subjects developed full-blown attacks of bronchospasm which was reversed with a saline solution placebo. The 40 control nonasthmatic subjects did not react.