The glucagonoma syndrome (necrolytic migratory erythema) and zinc
The glucagonoma syndrome (necrolytic migratory erythema) and zinc
复制标题
胰高血糖素瘤综合征（坏死性游走性红斑）与锌
DOI：
10.1056/nejm197610212951718
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发表时间：
1976
期刊：
影响因子：
--
通讯作者：
Hambidge Km
中科院分区：
文献类型：
--
作者：
R. B. Amon;K. H. Swenson;J. M. Hanifin;Hambidge Km
To the Editor: We agree with Drs. Tasman-Jones and Kay (N Engl J Med 293: 830, 1975) that the skin lesions that occur in patients with the glucagonoma syndrome closely mirror those present in patients with acute zinc deficiency. Recently, however, we had the opportunity to diagnose and manage a 19-year-old woman with the glucagonoma syndrome whose serum zinc level was 93 μg per 100 ml (normal, 68 to 110). The diagnosis was established on the basis of clinical signs (necrolytic migratory erythema and glossitis), a fivefold elevation of plasma glucagon levels and electron microscopy of surgical tissue demonstrating the.  No extract is available for articles shorter than 400 words.
