Clinical radioimmunodetection of cancer with radioactive antibodies to human chorionic gonadotropin.
Clinical radioimmunodetection of cancer with radioactive antibodies to human chorionic gonadotropin.
复制标题
使用人绒毛膜促性腺激素放射性抗体对癌症进行临床放射免疫检测。
作者：
D. Goldenberg;Ee Kim;F. Deland;Nagell Jr Van;N. Javadpour
将碘-131标记的山羊抗人绒毛膜促性腺激素（hCG）免疫球蛋白G抗体注射到分泌hCG的滋养细胞和生发性肿瘤患者中，可以通过外部伽玛射线显像检测和定位肿瘤。用这种方法切除其中一个转移瘤时，肿瘤/非肿瘤比率为39.29。该方法似乎为精确定位体内产生hcg的肿瘤提供了一种新的临床工具，即使其他临床方法无法识别肿瘤。
Injection of iodine-131-labeled goat immunoglobulin G antibody to human chorionic gonadotropin (hCG) into patients with hCG-secreting trophoblastic and germinal tumors permitted tumor detection and location by external gamma-ray scintigraphy. Excision of one of the metastatic tumors located by this method indicated a tumor/nontumor ration of 39.29. The method appears to offer a new clinical tool for precisely locating hCG-producing tumors in the body, even when tumor identification by other clinical methods has failed.