Clinical predictors of high risk histopathology in retinoblastoma
Clinical predictors of high risk histopathology in retinoblastoma
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DOI：
10.1002/pbc.23239
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发表时间：
2012-03-01
影响因子：
3.2
通讯作者：
Ghose, Supriyo
中科院分区：
文献类型：
--
作者：
Kashyap, Seema;Meel, Rachna;Ghose, Supriyo
背景以往的研究表明，视网膜母细胞瘤患者的临床特征，如青光眼和虹膜新生血管与摘除眼的高风险组织病理学发现（HRF）的发生率较高相关。在此，我们分析了在视网膜母细胞瘤摘除时的临床特征与HRF发生之间的关联，包括前房、虹膜、睫状体、脉络膜（大块）、巩膜、巩膜外组织、筛板外视神经和视神经切断端的侵袭。
Background Previous studies show that clinical features at presentation, in retinoblastoma patients, like glaucoma and neovascularization of iris are associated with a higher incidence of high risk histopathology findings (HRF) in enucleated eyes. Herein, we analyze association between clinical features at time of enucleation and occurrence of HRF including invasion of anterior chamber, iris, ciliary body, choroid (massive), sclera, extrascleral tissue, optic nerve beyond lamina cribrosa, and optic nerve cut end, in a large series of eyes enucleated for retinoblastoma.