The SARS-CoV-2 B.1.351/V2 variant is outgrowing the B.1.1.7/V1 variant in French regions in April 2021

The SARS-CoV-2 B.1.351/V2 variant is outgrowing the B.1.1.7/V1 variant in French regions in April 2021
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2021 年 4 月,法国地区 SARS-CoV-2 B.1.351/V2 变种的生长速度超过了 B.1.1.7/V1 变种

DOI:
10.1101/2021.05.12.21257130
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发表时间:
2021
影响因子:
1.4
通讯作者:
S. Alizon
S. Alizon
中科院分区:
--
文献类型:
--
作者:
B. Roquebert;S. Trombert;S. Haim;E. Lécorché;L. Verdurme;V. Foulongne;Mircea T. Sofonea;S. Alizon

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SARS-CoV-2变异威胁着我们控制COVID-19疫情的能力。我们分析了2021年4月12日至5月7日在法国收集的样本中进行的36,590种变异特异性RT-PCR检测,以比较变异传播。截至2021年1月至3月,我们发现V2变异株在某些地区(伊勒-德-法国为15.1至16.1%,奥茨-德-法国为16.1至18.8%)的传播优势明显高于V1。这种传播优势的转变与V2的免疫逃避能力和这些地区的高免疫水平一致。
SARS-CoV-2 variants threaten our ability to control COVID-19 epidemics. We analyzed 36,590 variant-specific RT-PCR tests performed on samples collected between April 12 and May 7, 2021 in France to compare variant spread. Contrarily to January to March 2021, we found that the V2 variant had a significant transmission advantage over V1 in some regions (15.1 to 16.1% in Ile-de-France and 16.1 to 18.8% in Hauts-de-France). This shift in transmission advantage is consistent with the immune evasion abilities of V2 and the high levels of immunization in these regions.
SARS-COV-2血统的估计可传播和影响B.1.1.7在英国。
DOI: 10.1126/science.abg3055
发表时间: 2021-04-09
期刊: Science (New York, N.Y.)
影响因子: --
作者:
Davies NG;Abbott S;Barnard RC;Jarvis CI;Kucharski AJ;Munday JD;Pearson CAB;Russell TW;Tully DC;Washburne AD;Wenseleers T;Gimma A;Waites W;Wong KLM;van Zandvoort K;Silverman JD;CMMID COVID-19 Working Group;COVID-19 Genomics UK (COG-UK) Consortium;Diaz-Ordaz K;Keogh R;Eggo RM;Funk S;Jit M;Atkins KE;Edmunds WJ
通讯作者: Edmunds WJ