Effects of intermittent inhalation exposures to mixed atmospheres of NO2 and H2SO4 on rabbit alveolar macrophages.
Effects of intermittent inhalation exposures to mixed atmospheres of NO2 and H2SO4 on rabbit alveolar macrophages.
复制标题
间歇性吸入 NO2 和 H2SO4 混合气体对兔肺泡巨噬细胞的影响。
DOI:
10.1080/15287398709531073
复制
发表时间:
1987
期刊:
影响因子:
--
通讯作者:
Schlesinger,RB
中科院分区:
文献类型:
--
作者:
Schlesinger,RB
Rabbits were exposed (2h/d) to atmospheres consisting of 0.5 mglrn3(0.3 μm) H2SOAplus NO2at either 0.3 (low) or 1 ppm (high). Animals were sacrificed 24 h after 2, 6, or 13 exposures, and cells were recovered from the lungs by bronchopulmonary lavage. Exposure to high NO2with acid resulted in an increase in neutrophils at all time points and an increase in phagocytic capacity of macrophages after two or six exposures. On the other hand, exposure to the low NO2with acid resulted in depressed phagocytic capacity and mobility. The results were compared with those for NO2or H2SO4given alone.