Recent Advances in Microwave-Based Dielectric Spectroscopy at the Cellular Level for Cancer Investigations
Recent Advances in Microwave-Based Dielectric Spectroscopy at the Cellular Level for Cancer Investigations
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DOI：
10.1109/tmtt.2013.2255885
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发表时间：
2013-05-01
影响因子：
4.3
通讯作者：
Fournie, Jean-Jacques
中科院分区：
文献类型：
--
作者：
Grenier, Katia;Dubuc, David;Fournie, Jean-Jacques
癌症仍然是世界上主要的死亡原因。为了克服这一问题，有必要开发新的分析工具，作为现有分析工具的补充，以便能够对疾病进行早期诊断，进行个性化治疗，并进一步了解癌症的基本机制。在这种背景下，在细胞和分子水平上进行的基于微波和毫米波的介电光谱学正在逐步出现，因为它允许对细胞培养生物介质中的细胞进行非侵入性和实时探测。本文给出了这一课题的最新进展，并对其各种资产进行了具体的突出说明。
Cancer remains a leading cause of death in the world. To overcome this problem, it is necessary to develop new analysis tools, in complementarity to existing ones, to enable the early diagnostic of the diseases, personalized treatment, and further fundamental cancer mechanisms understanding. In this context, microwave-based and millimeter-wave-based dielectric spectroscopy performed at the cellular and molecular levels is progressively emerging, as it permits the non-invasive and real-time probing of cells in their culture biological medium. The recent advances of this topic are given in this paper with a specific highlight of its various assets.