Quantitative assessment for stimulated saliva flow rate and buffering capacity in relation to different ages
Quantitative assessment for stimulated saliva flow rate and buffering capacity in relation to different ages
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DOI：
10.1016/j.jdent.2006.01.004
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发表时间：
2006-10-01
影响因子：
4.4
通讯作者：
Nomura, Satoshi
中科院分区：
文献类型：
--
作者：
Moritsuka, Michiyo;Kitasako, Yuichi;Nomura, Satoshi
目的：为了评估唾液流速和缓冲能力，使用定量pH测量在三个广泛的年龄groups.Methods：人口组成的117例患者分为三个年龄组：青年，中年，老年组。测量咀嚼口香糖后刺激唾液的体积。用0.1N HCl滴定唾液样品以评价缓冲能力。使用手持式pH计直接测量唾液pH变化。在50 μ L滴定HCl的点处，个体唾液缓冲能力被分为以下三个类别之一：高缓冲能力（pH 5.5以上），中等缓冲能力（pH 5.5至4.5），以及低缓冲能力（低于pH 4.5）。chi（2）-检验表明，缓冲能力组中的个体比例分布在年龄组之间没有统计学差异（p > 0.05）。单因素方差分析和Tukey's HSD检验显示，青年组刺激性全唾液流率显著大于中老年组（p < 0.05）。双因素方差分析显示，独立变量缓冲能力和年龄组之间没有显著的交互作用（F = 0.419，p = 0.7950）。单因素方差分析和Tukey的HSD测试表明，流速显示三个年龄和缓冲能力groups.Conclusions之间的显着差异：虽然有限数量的主题进行了调查，在这项研究中，定量唾液评估是有用的筛选方法，为不同年龄的患者，以确定低唾液流速和/或缓冲能力。(C)2006爱思唯尔有限公司保留所有权利。
Objectives: To evaluate salivary flow rate and buffering capacity using a quantitative pH measurement among three broad age groups.Methods: The population consisting of 117 patients was classified into three age groups: young, middle-aged, and elderly group. The volume of stimulated saliva after chewing gum was measured. Saliva samples were titrated with 0.1N HCl to evaluate the buffering capacity. Saliva pH change was measured directly using a hand-held pH meter. At the point of 50 mu L of titrated HCl, individual salivary buffering capacities were ranked into one of the following three categories; high buffering capacity (above pH 5.5), medium buffering capacity (from pH 5.5 to 4.5), and low buffering capacity (below pH 4.5).Results: chi(2)-test showed that the proportional distribution of individuals in the three buffering capacity groups was not statistically different among the age groups (p > 0.05). One-way ANOVA and Tukey's HSD test showed the flow rate of stimulated whole saliva in the young group was significantly greater than that of the middle-aged and elderly groups (p < 0.05). Two-way ANOVA showed there was no significant interaction between the independent variables buffering capacity and age group (F = 0.419, p = 0.7950). One-way ANOVA and Tukey's HSD test indicated the flow rate showed significant differences among the three age and buffering capacity groups.Conclusions: Although a limited number of subjects were investigated in this study, the quantitative saliva assessment is useful as a screening method for different ages to identify patients with a low saliva flow rate and/or buffering capacity. (C) 2006 Elsevier Ltd. All rights reserved.