Imported malaria: a possible threat to the elimination of malaria from Sri Lanka?
Imported malaria: a possible threat to the elimination of malaria from Sri Lanka?
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DOI：
10.1111/tmi.12097
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发表时间：
2013-06-01
影响因子：
3.3
通讯作者：
Abeyasinghe, R. R.
中科院分区：
文献类型：
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作者：
Galappaththy, G. N. L.;Fernando, S. D.;Abeyasinghe, R. R.
目的讨论输入性疟疾的流行病学方面和斯里兰卡2008-2011年报告的输入性疟疾病例的潜在影响，包括可能的疾病复发，方法使用国家疟疾数据库评估有关可能获得感染的国家，疟原虫种类，斯里兰卡入境和诊断之间的天数，结果加强疟疾监测后，4年间共报告输入性疟疾病例152例，比前一年增加176%。大多数输入性疟疾感染是由斯里兰卡国民主要从南亚，特别是印度获得的。间日疟原虫占感染的64%。大约50%的病例是在西部省确诊的。从在斯里兰卡下船到疟疾诊断的平均时间为3.6天。根据国家指南对患者进行管理和治疗。82%的患者进行了随访，28天，以确保寄生虫clearance.CONCLUSIONS有可能增加风险的疟疾重新引进到该国的进口病例。监测活动的加强和国际旅行的增加促使记录的病例数增加。如果该国要防止国内传播的重新建立，就需要进一步加强监测，特别是监测和及时处理输入性疟疾。报告还强调了建立有效应对机制以应对输入性疟疾的重要性。
OBJECTIVE To discuss epidemiological aspects of imported malaria and the potential impact of imported malaria cases reported in Sri Lanka 2008-2011 in terms of a possible resurgence of the disease.METHODS The national malaria database was used to assess details regarding country where the infection was possibly acquired, species of Plasmodium, number of days lapsed between disembarkation in Sri Lanka and diagnosis, compliance with national treatment guidelines including percentage of patients followed up as per the national guidelines.RESULTS After the strengthening of malaria surveillance, during the 4-year period, 152 imported malaria cases were recorded: an increase of 176% in the number of cases. Most of the imported malaria infections were acquired by Sri Lankan Nationals mainly from South Asia, especially India. Plasmodium vivax accounted for 64% of the infections. Approximately 50% of the cases were diagnosed in the Western Province. The average period from disembarkation in Sri Lanka to malaria diagnosis was 3.6 days. Patients were managed and treated according to the national guidelines. 82% of the patients were followed up for 28 days to ensure parasite clearance.CONCLUSIONS There is a possible increasing risk of re-introduction of malaria to the country from imported cases. Enhanced surveillance activities and the increase in international travel have contributed to an increase in recorded case numbers. There is a need to further strengthen surveillance, especially for monitoring and timely addressing of imported malaria, if the country is to prevent the re-establishment of transmission within. The importance of having an efficient response mechanism to deal with imported malaria is also highlighted.