Temperature modulation of the stereochemistry of enzymatic catalysis: Prospects for exploitation
Temperature modulation of the stereochemistry of enzymatic catalysis: Prospects for exploitation
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DOI：
10.1016/0167-7799(96)80908-5
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发表时间：
1996-01-01
影响因子：
17.3
通讯作者：
Phillips, RS
中科院分区：
文献类型：
--
作者：
Phillips, RS
利用物理变量来控制酶催化反应的立体化学结果是生物催化研究中的一个热点。温度对立体化学的影响直到最近才被理解和充分认识。本文阐述了温度对酶促反应立体化学的影响，并对温度调控酶促反应立体化学过程的应用前景进行了展望。
The use of physical variables to control the stereochemical outcome of enzyme-catalysed reactions is of great interest in biocatalysis. The effects of temperature on stereochemistry were not understood and fully appreciated until recently. This article indicates how temperature can influence the stereochemistry of enzymatic reactions, and reviews the prospects for future applications of temperature modulation of the stereochemical course of enzymatic reactions.