Aerobic capacity, muscle strength and health-related quality of life before and after orthotopic liver transplantation: preliminary data of an Austrian transplantation centre.
Aerobic capacity, muscle strength and health-related quality of life before and after orthotopic liver transplantation: preliminary data of an Austrian transplantation centre.
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原位肝移植前后的有氧能力、肌肉力量和健康相关的生活质量：奥地利移植中心的初步数据。
DOI：
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发表时间：
2006
影响因子：
3.5
通讯作者：
G. Wiesinger
中科院分区：
文献类型：
--
作者：
K. Pieber;R. Crevenna;M. Nuhr;M. Quittan;M. Peck‐Radosavljevic;V. Fialka;G. Wiesinger
目的
原位肝移植前患者的体能状态通常会下降，这会影响他们的日常生活和社会参与。这项初步研究的目的是评估耐力，肌肉力量，和生活质量之前和之后的原位肝移植患者在奥地利移植中心。
科目
15例患者（男性/女性= 10：5）被纳入初步研究。
方法
在原位肝移植术前和术后（1-2个月后）评估运动试验、膝伸肌和握力强度试验以及生活质量（SF-36健康调查表）。
结果
无氧阈氧摄取量（VO 2AT）和股四头肌等速肌力测试从基线、移植前到原位肝移植后随访无显著变化。在原位肝移植之前，生活质量在功能状态、情感角色、活力和总体健康感知方面受到阻碍。原位肝移植术后，本研究人群的社会功能（p=0.032）、活力（p=0.006）、心理健康（p=0.004）和总体健康感知（p=0.002）均有显著改善。
结论
这项包括奥地利移植中心人群的试点研究的结果表明，原位肝移植前后患者的身体机能缺陷以及生活质量下降。
OBJECTIVE
Patients before orthotopic liver transplantation usually show a reduced physical performance status, which impacts on their daily life and social participation. This pilot study aimed to evaluate endurance capacity, muscle strength, and quality of life before and after orthotopic liver transplantation in patients in an Austrian transplantation centre.
SUBJECTS
Fifteen patients (male/female = 10:5) were included in the pilot study.
METHODS
Exercise testing, strength testing of knee extensor muscles and of handgrip, and quality of life (SF-36 health survey) were assessed before and after orthotopic liver transplantation (after 1-2 months).
RESULTS
The oxygen uptake at the anaerobic threshold (VO2AT) and isokinetic strength testing of quadriceps femoris muscle did not change significantly from baseline, before transplantation to follow-up after orthotopic liver transplantation. Before orthotopic liver transplantation, quality of life was hampered concerning functional status, emotional role, vitality, and general health perception. Significant improvements of social functioning (p=0.032), vitality (p=0.006), mental health (p=0.004) and general health perception (p=0.002) could be found for this study population after orthotopic liver transplantation.
CONCLUSION
The results of this pilot study including a population of an Austrian transplantation centre indicate deficits of physical performance as well as reduced quality of life in patients before and after orthotopic liver transplantation.
今天进行肝移植。
影响因子：
10.5
作者：
Roberts,JP;Forsmark,C;Lake,JR;Ascher,NL
通讯作者：
Ascher,NL