Percentage of Gestational Diabetes Mellitus Attributable to Overweight and Obesity
Percentage of Gestational Diabetes Mellitus Attributable to Overweight and Obesity
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DOI：
10.2105/ajph.2009.172890
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发表时间：
2010-06-01
影响因子：
12.7
通讯作者：
Dietz, Patricia
中科院分区：
文献类型：
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作者：
Kim, Shin Y.;England, Lucinda;Dietz, Patricia
目标.我们计算了妊娠期糖尿病（GDM）归因于超重和肥胖的百分比。方法.我们分析了2004年至2006年的数据，从7个州使用怀孕风险评估监测系统链接到修订后的2003年出生证明信息。我们使用逻辑回归来估计孕前体重指数（BMI）和GDM之间的关联程度，并计算GDM归因于超重和肥胖的百分比。结果按BMI分类的GDM患病率如下：（13-18.4 kg/m（2）），0.7%;正常体重（18.5-24.9 kg/m2），2.3%;超重（25-29.9 kg/m2），4.8%;肥胖（30-34.9 kg/m2），5.5%;和极度肥胖（35-64.9 kg/m2），11.5%。超重、肥胖和极度肥胖导致的GDM患病率分别为15.4%（95%置信区间[CI]=8.6，22.2）、9.7%（95% CI =5.2，14.3）和21.1%（CI =15.2，26.9）。总体人群归因分数为46.2%（95%C1 =-36.1，56.3）。结论.如果所有超重和肥胖妇女（BMI为25 kg/m2或以上）的GDM风险与正常体重妇女相等，则近一半的GDM病例可以预防。应加强公共卫生工作，通过促进育龄妇女的体育活动和健康饮食来降低孕前体重指数。(Am J公共卫生。2010;100：1047-1052。doi：10.2105/AJPH.2009.172890）
Objectives. We calculated the percentage of gestational diabetes mellitus (GDM) attributable to overweight and obesity. Methods. We analyzed 2004 through 2006 data from 7 states using the Pregnancy Risk Assessment Monitoring System linked to revised 2003 birth certificate information. We used logistic regression to estimate the magnitude of the association between prepregnancy body mass index (BMI) and GDM and calculated the percentage of GDM attributable to overweight and obesity. Results. GDM prevalence rates by BMI category were as follows: underweight (13-18.4 kg/m(2)), 0.7%; normal weight (18.5-24.9 kg/m(2)), 2.3%; overweight (25-29.9 kg/m(2)), 4.8%; obese (30-34.9 kg/m(2)), 5.5%; and extremely obese (35-64.9 kg/m(2)), 11.5%. Percentages of GDM attributable to overweight, obesity, and extreme obesity were 15.4% (95% confidence interval [CI]=8.6, 22.2), 9.7% (95% C1=5.2, 14.3), and 21.1% (CI =15.2, 26.9), respectively. The overall population-attributable fraction was 46.2% (95% C1=-36.1, 56.3). Conclusions. If all overweight and obese women (BMI of 25 kg/m(2) or above) had a GDM risk equal to that of normal-weight women, nearly half of GDM cases could be prevented. Public health efforts to reduce prepregnancy BMI by promoting physical activity and healthy eating among women of reproductive age should be intensified. (Am J Public Health. 2010;100:1047-1052. doi:10.2105/AJPH.2009.172890)