Regional assignment of the polymorphic probe D3S3 to 3p14 by molecular hybridization.

Regional assignment of the polymorphic probe D3S3 to 3p14 by molecular hybridization.
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通过分子杂交将多态性探针 D3S3 区域分配至 3p14。

DOI:
10.1159/000132254
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发表时间:
1986
期刊:
Cytogenetics and cell genetics
影响因子:
--
通讯作者:
Scoggin,CH
Scoggin,CH
中科院分区:
--
文献类型:
--
作者:
Gerber,MJ;Miller,YE;Drabkin,HA;Scoggin,CH

文献摘要

被引文献

相似文献

多态性DNA探针D3 S3通过使用人3号染色体/仓鼠体细胞杂交缺失板的分子杂交被指定为3 p14。这是第一次区域分配的多态性探针的短臂3号染色体。这种探针似乎是接近3号染色体脆性位点,因此,可能证明有用的特征3 p染色体畸变发生在各种恶性疾病。
The polymorphic DNA probe D3S3 was assigned to 3pl4 by molecular hybridization using a human chromosome 3/hamster somatic cell hybrid deletion panel. This is the first regional assignment of a polymorphic probe to the short arm of chromosome 3. This probe appears to be proximal to the chromosome 3 fragile site and, therefore, may prove useful in characterizing the 3p chromosomal aberrations that occur in various malignant diseases.