Formation of periodic nanostructures using a femtosecond laser to control cell spreading on titanium
Formation of periodic nanostructures using a femtosecond laser to control cell spreading on titanium
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DOI：
10.1007/s00340-015-6082-4
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发表时间：
2015-06-01
影响因子：
2.1
通讯作者：
Hanawa, T.
中科院分区：
文献类型：
--
作者：
Shinonaga, T.;Tsukamoto, M.;Hanawa, T.
虽然钛(Ti)是一种常见的生物材料，但利用飞秒激光形成周期性结构来控制细胞扩散，应该会改善其生物相容性。在这里，我们研究了在钛板表面形成的周期性纳米结构对细胞扩展的影响。利用波长为775 nm的飞秒激光形成了周期为590 nm的纳米结构。在没有周期结构的平板上，细胞扩散缺乏一定的方向，而在具有周期结构的钛板上，细胞沿着凹槽扩散，这表明利用飞秒激光形成周期结构可以控制细胞的扩散。
Although titanium (Ti) is a common biomaterial, controlling cell spreading by forming periodic structures using a femtosecond laser should improve its biocompatibility. Herein we investigate the influence of periodic nanostructures formed on the surface of a Ti plate on cell spreading. Nanostructures with a periodicity of 590 nm are formed using a femtosecond laser with a wavelength of 775 nm. Cell spreading on the plate without period structures lacks a definite direction, whereas cell spreading on the Ti plate with periodic structures occurs along the grooves, suggesting that forming periodic structures via a femtosecond laser can control cell spreading.