Association of Testosterone Levels With Anemia in Older Men A Controlled Clinical Trial
Association of Testosterone Levels With Anemia in Older Men A Controlled Clinical Trial
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DOI：
10.1001/jamainternmed.2016.9540
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发表时间：
2017-04-01
影响因子：
39
通讯作者：
Ellenberg, Susan S.
中科院分区：
文献类型：
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作者：
Roy, Cindy N.;Snyder, Peter J.;Ellenberg, Susan S.
在三分之一患有贫血的老年男性中，睾酮的重要性尚未被发现。目的确定65岁或以上男性的睾酮水平明显较低且有不明原因的贫血是否会增加他们的血红蛋白浓度。设计、设置和参与者一项双盲、安慰剂对照试验，通过最小化治疗分配，使用788名平均睾酮水平低于275 ng/dL的65岁或以上男性。在788名参与者中，126人患有贫血(血红蛋白
IMPORTANCE In one-third of older men with anemia, no recognized cause can be found.OBJECTIVE To determine if testosterone treatment of men 65 years or older with unequivocally low testosterone levels and unexplained anemia would increase their hemoglobin concentration.DESIGN, SETTING, AND PARTICIPANTS A double-blinded, placebo-controlled trial with treatment allocation by minimization using 788 men 65 years or older who have average testosterone levels of less than 275 ng/dL. Of 788 participants, 126 were anemic (hemoglobin