Orienting patients to greater opioid safety: models of community pharmacy-based naloxone
Orienting patients to greater opioid safety: models of community pharmacy-based naloxone
复制标题
DOI：
10.1186/s12954-015-0058-x
复制
发表时间：
2015-08-06
影响因子：
4.4
通讯作者：
Walley, Alexander Y.
中科院分区：
文献类型：
--
作者：
Green, Traci C.;Dauria, Emily F.;Walley, Alexander Y.
在美国，成人伤害死亡的主要原因是药物过量，其中大部分涉及处方阿片类药物。在美国以外，吸毒过量导致的死亡人数也在上升，吸毒过量是吸毒者死亡的主要原因。要降低过量风险，同时在有医学指征时保持获得处方阿片类药物的机会，需要仔细考虑阿片类药物的处方和分配方式、患者如何使用它们、它们如何与其他药物相互作用以及如何安全储存。药剂师是训练有素的专业人员，擅长检测和管理用药错误、药物相互作用、安全配药和患者咨询，是解决美国和全球用药过量问题的未充分利用的资产。药房提供了一个高收益的环境，患者和护理人员客户可以获得纳洛酮（一种阿片拮抗剂，可逆转阿片类药物过量和过量预防咨询）。本案例研究简要描述并提供了两个针对美国各州的基于药房的纳洛酮创新政策模型的示例，这些模型的实施旨在减少过量事件并提高阿片类药物的安全性：合作药房实践协议和药房常规。
The leading cause of adult injury death in the USA is drug overdose, the majority of which involves prescription opioid medications. Outside of the USA, deaths by drug overdose are also on the rise, and overdose is a leading cause of death for drug users. Reducing overdose risk while maintaining access to prescription opioids when medically indicated requires careful consideration of how opioids are prescribed and dispensed, how patients use them, how they interact with other medications, and how they are safely stored. Pharmacists, highly trained professionals expert at detecting and managing medication errors and drug-drug interactions, safe dispensing, and patient counseling, are an under-utilized asset in addressing overdose in the US and globally. Pharmacies provide a high-yield setting where patient and caregiver customers can access naloxone-an opioid antagonist that reverses opioid overdose-and overdose prevention counseling. This case study briefly describes and provides two US state-specific examples of innovative policy models of pharmacy-based naloxone, implemented to reduce overdose events and improve opioid safety: Collaborative Pharmacy Practice Agreements and Pharmacy Standing Orders.