INSULA OF THE OLD-WORLD MONKEY .3. EFFERENT CORTICAL OUTPUT AND COMMENTS ON FUNCTION
INSULA OF THE OLD-WORLD MONKEY .3. EFFERENT CORTICAL OUTPUT AND COMMENTS ON FUNCTION
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DOI：
10.1002/cne.902120104
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发表时间：
1982-01-01
影响因子：
2.5
通讯作者：
MUFSON, EJ
中科院分区：
文献类型：
--
作者：
MESULAM, MM;MUFSON, EJ
小脑向皮质区发送神经传出，从皮质区接收相互的传入投射。集体考虑的传入和传出表明，在嗅觉，味觉，躯体感觉（SI和SII）和听觉（AI和AII）的方式与主要的感觉区的连接。此外，还与视觉（TEm）、听觉（颞上平面）和躯体感觉（后顶叶皮层）的关联区、运动旁皮层（6区，可能还有MII）、多模态关联皮层以及眶、颞极和扣带回的广泛边缘区有联系。这些连接的地形分布表明，后背侧岛叶专门负责听觉-躯体感觉-骨骼运动功能，而前腹侧岛叶则与嗅觉-味觉-自主神经功能相关。大部分的小脑，特别是前腹侧部分，与边缘系统结构有广泛的相互连接。通过与杏仁核的连接，杏仁核为躯体感觉、听觉、味觉、嗅觉和内脏感觉提供了一条到达边缘系统的通路。与颗粒区相连的皮质区在结构上也是颗粒状的，而几乎所有的无颗粒区的连接都来自于异皮质、无颗粒或颗粒异常区。岛屿教派的建筑与它们所连接的地区之间存在着对应关系。颞极区和外侧眶区紧密相连。外侧眶皮质的许多皮质连接与外侧眶皮质的皮质连接非常相似。这些共同的连接模式支持的结论，岛眶颞极组成部分的边缘脑是一个完整的单位的大脑组织。
The insula sends neural efferents to cortical areas from which it receives reciprocal afferent projections. A collective consideration of afferents and efferents indicates that the insula has connections with principal sensory areas in the olfactory, gustatory, somesthetic (SI and SII) and auditory (AI and AII) modalities. There are additional connections with association areas for the visual (TEm), auditory (supratemporal plane) and somesthetic (posterior parietal cortex) modalities; with paramotor cortex (area 6 and perhaps MII); with polymodal association cortex; and with a wide range of paralimbic areas in the orbital, temporopolar and cingulate areas. The topographic distribution of these connections suggests that the posterodorsal insula is specialized for auditory-somesthetic-skeletomotor function, whereas the anteroventral insula is related to olfactory-gustatory-autonomic function. Most of the insula, especially its anteroventral portions, have extensive interconnections with limbic structures. Through its connections with the amygdala, the insula provides a pathway for somatosensory, auditory, gustatory, olfactory and visceral sensations to reach the limbic system. The cortical areas connected with the granular sector of the insula are also granular in architecture, whereas virtually all the connections of the agranular insula arise from allocortical, agranular or dysgranular areas. There is a correspondence between the architecture of insular sectars and the areas with which they have connections. The insula is heavily interconnected with temporopolar and lateral orbital areas. Many cortical connections of the lateral orbital cortex are quite similar to those of the insula. These common connectivity patterns support the conclusion that the insulo-orbito-temporopolar component of the paralimbic brain is an integrated unit of cerebral organization.