Bradycardia, increased cardiac output, and reversal of pulmonary hypertension in altitude natives living at sea level.
Bradycardia, increased cardiac output, and reversal of pulmonary hypertension in altitude natives living at sea level.
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DOI：
10.1136/hrt.33.5.647
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发表时间：
1971-09
影响因子：
--
通讯作者：
F. Sime;D. Peñaloza;L. Ruiz
中科院分区：
文献类型：
--
作者：
F. Sime;D. Peñaloza;L. Ruiz
对11名高海拔地区健康男性青年在原居住地和在海平面居住2年后进行了血液动力学研究。这项研究旨在确定高原人的心率、心输出量和肺动脉压对低氧刺激抑制的长期影响。为了比较的目的，在高海拔吸氧的影响也进行了研究。心率在海平面下降，大多数病例出现心动过缓。心率的下降可能与副交感神经系统的优势增加有关。
Eleven healthy young men native to high altitude underwent haemodynamic studies at their original place of residence and after two years' residence at sea level. The investigation sought to determine the long-term effects of the suppression of the hypoxic stimulus upon heart rate, cardiac output, and pulmonary artery pressure of highlanders. For comparative purposes the influence of oxygen inhalation at high altitude was also studied. The heart rate fell at sea level and bradycardia was seen in most of the cases. The fall in heart rate is probably related to an increase in the predominance of the parasympathetic nervous sys-