Assessment of local tissue water in the arms and trunk of breast cancer survivors with and without upper extremity lymphoedema
Assessment of local tissue water in the arms and trunk of breast cancer survivors with and without upper extremity lymphoedema
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DOI：
10.1111/cpf.12541
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发表时间：
2019-01-01
影响因子：
1.8
通讯作者：
Miaskowski, Christine
中科院分区：
文献类型：
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作者：
Mazor, Melissa;Smoot, Betty J.;Miaskowski, Christine
由于缺乏信息的局部组织水（LTW）在上肢和躯干的女性乳腺癌手术后，本研究的目的是比较组织介电常数（TDC）值之间的乳腺癌幸存者患侧和未患侧上肢淋巴水肿（LE）。使用TDC方法评估了上肢三个部位、侧胸三个部位和背部两个部位的LTW差异。其他指标包括人口统计学和临床特征、臂围和生物阻抗分析。对于112名无LE的幸存者，在第一背侧蹼间隙、前臂腹侧和上臂、上背部和下背部的患侧和未患侧之间的TDC值没有差异。与健侧相比，患侧上、中、下侧胸的TDC值显著较高。对于78名LE幸存者，与健侧相比，除了手蹼空间外，所有评估部位的患侧TDC均显著较高。我们的研究结果支持使用TDC方法检测乳腺癌治疗后LE幸存者上肢和躯干水肿的差异。LTW的测量可以提供一个有用的方法来确定躯干以及四肢LE。发现躯干水肿的早期迹象的能力可能会导致乳腺癌幸存者的先发制人的干预措施。
Given the paucity of information on local tissue water (LTW) in the upper extremity and trunk of women after breast cancer surgery, the purpose of this study was to compare tissue dielectric constant (TDC) values between the affected and unaffected sides of breast cancer survivors with and without upper extremity lymphoedema (LE). Differences in LTW were assessed using the TDC method for three sites in the upper limbs, three sites in the lateral thorax and two sites on the back. Additional measures included demographic and clinical characteristics, arm circumference and bioimpedance analysis. For the 112 survivors without LE, no differences in TDC values were found between the affected and unaffected sides for the first dorsal web space, ventral forearm and upper arm, and upper and lower back. Compared to the unaffected side, TDC values were significantly higher on the affected side for the upper, mid and lower lateral thorax. For the 78 survivors with LE, compared to the unaffected side, TDC was significantly higher on the affected side for all of the sites evaluated except the hand web space. Our findings support the use of the TDC method to detect differences in upper extremity and truncal oedema in survivors with LE following breast cancer treatment. Measurement of LTW may provide a useful method to determine truncal as well as extremity LE. The ability to detect early signs of truncal oedema may lead to pre-emptive interventions in breast cancer survivors.