ISLANDS OF CALLEJA - ORGANIZATION AND CONNECTIONS
ISLANDS OF CALLEJA - ORGANIZATION AND CONNECTIONS
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DOI：
10.1002/cne.901810209
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发表时间：
1978-01-01
影响因子：
2.5
通讯作者：
MOORE, RY
中科院分区：
文献类型：
--
作者：
FALLON, JH;RILEY, JN;MOORE, RY
大鼠Calleja岛（IC）由嗅结节多形层的7个小颗粒细胞群和沿着隔、丘脑核和斜角带核之间的1个大颗粒细胞群组成。IC和周围细胞的细胞结构和神经元形态，研究使用Nissl染色和Golgi-Kopsch材料，进行了描述。此外，使用荧光组织化学，放射自显影示踪法，顺行和逆行辣根过氧化物酶法分析了IC的传入和传出联系。拓扑组织的投影IC从黑质腹侧被盖区的多巴胺含细胞表现出乙醛酸荧光组织化学方法和放射自显影示踪技术。顺行和逆行的辣根过氧化物酶的研究提供了证据，相互的，地形组织之间的互连IC和隔膜，核丘脑，杏仁核和梨状皮质。这些观察结果表明，IC构成了一个独特的人口颗粒细胞，位于嗅结节，由中脑多巴胺神经元支配，并与基底前脑的嗅觉和非嗅觉组件互连。
The islands of Calleja (IC) in the rat are composed of 7 small groups of granule cells in the polymorph layer of the olfactory tubercle and 1 large group, the insula magna, which lies along the border between septum, nucleus accumbens and nucleus of the diagonal band. The cytoarchitecture and neuronal morphology of the IC and surrounding cells, studied using Nissl-stained and Golgi-Kopsch material, are described. In addition, the afferent and efferent connections of the IC were analyzed using fluorescence histochemistry, the autoradiographic tracing method, and the anterograde and retrograde horseradish peroxidase methods. Topographically organized projections to the IC from the dopamine-containing cells of the substantia nigra-ventral tegmental area are demonstrated by the glyoxylic acid fluorescence histochemical method and the autoradiographic tracing technique. Anterograde and retrograde horseradish peroxidase studies provide evidence for reciprocal, topographically organized interconnections between the IC and the septum, nucleus accumbens, amygdala and piriform cortex. These observations indicate that the IC constitute a unique population of granule cells, located in the olfactory tubercle, innervated by dopamine neurons of the mesencephalon and interconnected with olfactory and non-olfactory components of the basal forebrain.