The two hit hypothesis in the antiphospholipid syndrome: acute ischaemic heart involvement after valvular replacement despite anticoagulation in a patient with secondary APS
The two hit hypothesis in the antiphospholipid syndrome: acute ischaemic heart involvement after valvular replacement despite anticoagulation in a patient with secondary APS
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DOI：
10.1191/0961203303lu445cr
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发表时间：
2003-01-01
期刊：
影响因子：
2.6
通讯作者：
Meroni, PL
中科院分区：
文献类型：
--
作者：
Bordin, G;Boldorini, R;Meroni, PL
一个病人与抗磷脂综合征（APS），其中非致死性心肌梗死继发瓣膜心脏置换术后，尽管抗凝，是描述。该报告进一步强调了伴随风险因素在诱发血栓事件中的作用，并指出心脏手术可能是APS患者心肌缺血损伤的潜在主要风险。
A patient with the antiphospholipid syndrome (APS), in whom a nonfatal myocardial infarction ensued after valvular heart replacement despite anticoagulation, is described. The report further stresses the role of concomitant risk co-factors in inducing thrombotic events and points out that cardiosurgery might represent a potential major risk for myocardial ischaemic damage in APS.