Harnessing Dendritic Cells: Next Frontier for Durable Immune Control in Myeloma.

Harnessing Dendritic Cells: Next Frontier for Durable Immune Control in Myeloma.
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利用树突状细胞:骨髓瘤持久免疫控制的下一个前沿。

DOI:
10.1158/1078-0432.ccr-23-2292
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发表时间:
2023
期刊:
Clinical cancer research : an official journal of the American Association for Cancer Research
影响因子:
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通讯作者:
Dhodapkar,MadhavV
Dhodapkar,MadhavV
中科院分区:
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文献类型:
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作者:
Dhodapkar,MadhavV

文献摘要

相似文献

包括T细胞重定向在内的基于免疫的方法已经改变了骨髓瘤的治疗前景。树突状细胞(DC)的注射导致骨髓瘤接种患者的免疫应答的诱导。这些研究为未来利用DC增强肿瘤免疫力并改善骨髓瘤结局的联合策略铺平了道路。参见Freeman等人的相关文章,第4575页
Immune-based approaches including T-cell redirection have transformed the therapeutic landscape in myeloma. Injection of dendritic cells (DC) led to the induction of immune responses in vaccinated patients with myeloma. These studies pave the way for future combination strategies harnessing DCs to enhance tumor immunity and improve outcomes in myeloma.See related article by Freeman et al., p. 4575