Quality of life, employment status, and anginal symptoms after coronary angioplasty or bypass surgery - 3-year follow-up in the randomized intervention treatment of angina (RITA) trial
Quality of life, employment status, and anginal symptoms after coronary angioplasty or bypass surgery - 3-year follow-up in the randomized intervention treatment of angina (RITA) trial
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DOI：
10.1161/01.cir.94.2.135
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发表时间：
1996-07-15
期刊：
影响因子：
37.8
通讯作者：
Hampton, JR
中科院分区：
文献类型：
--
作者：
Pocock, SJ;Henderson, RA;Hampton, JR
背景 心绞痛随机干预治疗 (RITA) 试验比较了 1011 名心绞痛患者的经皮腔内冠状动脉成形术 (PTCA) 和冠状动脉搭桥手术 (CABG) 的初始策略。本报告评估了这些血运重建手术对心绞痛、生活质量（根据诺丁汉健康档案）和 3 年以上随访的就业的影响。 方法和结果 两种干预措施在所有生活质量维度（能量疼痛、情绪反应、睡眠、社交孤立和活动能力）以及日常生活的七个方面均产生了显着改善。 2 岁时患有心绞痛的患者比无心绞痛的患者有更多的生活质量受损，后者的健康状况与人群正常水平相似。这反映了心绞痛等级和生活质量之间在基线上的密切联系。与 CABG 患者相比，PTCA 患者的生活质量受损稍大，因为他们患心绞痛的几率明显更高，尤其是 6 个月后。就业状况调查主要针对60岁以下男性。 PTCA 患者恢复工作的时间较早（2 个月时恢复工作的比例为 40%，而 CABG 患者恢复工作的比例为 10%），但后者晚了 5 个月。 2 年后，分别有 22% 和 26% 的 CABG 和 PTCA 患者因心脏原因无法工作。 2岁时患有心绞痛的患者比没有患心绞痛的患者更有可能失业。结论 PTCA或CABG大大减轻了心绞痛对生活质量和失业的影响。通过 CABG 可以更成功地避免心绞痛，但 PTCA 可以更快地恢复工作。这两种干预策略都会在几年内对生活质量和就业产生类似的好处。
Background The Randomized Intervention Treatment of Angina (RITA) trial compares initial policies of percutaneous transluminal coronary angioplasty (PTCA) and coronary artery bypass graft surgery (CABG) in 1011 patients with angina. This report assesses the impact of these revascularization procedures on angina, quality of life (according to the Nottingham Health Profile), and employment over 3 years of follow-up.Methods and Results Both interventions produced marked improvement in all quality-of-life dimensions (energy pain, emotional reactions, sleep, social isolation, and mobility) and seven aspects of daily living. Patients with angina at 2 years had more quality-of-life impairment than angina-free patients, whose perceived health was similar to population norms. This reflects the close Link at baseline between angina grade and quality of life. The slightly greater impairment of quality of life in PTCA compared with CABG patients is a result of their significantly higher chances of having angina, especially after 6 months. Employment status was investigated mainly for men less than or equal to 60 years old. PTCA patients returned to work sooner (40% at 2 months compared with 10% of CABG patients), but the latter caught up by 5 months. After 2 years, 22% and 26% of CABG and PTCA patients, respectively, were not working for cardiac reasons. Patients with angina at 2 years were much more likely to be unemployed than those without.Conclusions The impact of angina on quality of life and unemployment is greatly alleviated by PTCA or CABG. Angina is avoided more successfully with CABG, but PTCA offers a speedier return to work. Both intervention strategies then produce similar benefits for quality of life and employment over several years.