Bubble dynamics and size distributions during focused ultrasound insonation
Bubble dynamics and size distributions during focused ultrasound insonation
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DOI：
10.1121/1.1823251
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发表时间：
2004-12-01
影响因子：
2.4
通讯作者：
Holt, RG
中科院分区：
文献类型：
--
作者：
Yang, XM;Roy, RA;Holt, RG
超声能量在组织中的沉积可由于局部加热而导致组织损伤。对于高于临界阈值的压力，将发生空化，从而在局部区域中引起大得多的热能沉积。本文建立了一个非线性气泡动力学模型，数值研究了聚焦超声（HIFU）辐照过程中气泡的振荡和气泡增强加热。该模型被应用于计算两个阈值依赖的现象发生的非线性振荡气泡：形状不稳定和增长整流扩散。这些不稳定性反过来被示出放置在依赖于时间的气泡尺寸分布上的物理边界，并且因此热能沉积。(C)2004年，美国声学学会。
The deposition of ultrasonic energy in tissue can cause tissue damage due to local heating. For pressures above a critical threshold, cavitation will occur, inducing a much larger thermal energy deposition in a local region. The present work develops a nonlinear bubble dynamics model to numerically investigate bubble oscillations and bubble-enhanced heating during focused ultrasound (HIFU) insonation. The model is applied to calculate two threshold-dependent phenomena occurring for nonlinearly oscillating bubbles: Shape instability and growth by rectified diffusion. These instabilities in turn are shown to place physical boundaries on the time-dependent bubble size distribution, and thus the thermal energy deposition. (C) 2004 Acoustical Society of America.