Sensory perception in Parkinson disease
Sensory perception in Parkinson disease
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DOI：
10.1001/archneur.1997.00550160080020
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发表时间：
1997-04-01
影响因子：
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通讯作者：
Aminoff, MJ
中科院分区：
文献类型：
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作者：
Jobst, EE;Melnick, ME;Aminoff, MJ
目的：为了确定是否有一个复杂的感觉障碍，可能会导致运动缺陷的帕金森病患者。设计：比较性能的患者和健康的，年龄和性别匹配的科目在测试的各种感觉功能。设置：中心的人类表现和测试在一所大学医院和研究中心。参与者：10名帕金森病受试者和10名对照受试者的年龄和性别相匹配。主要结果测量：感觉统合和实践测试的4个子测试的表现：手指识别，书写感觉，触觉刺激定位和动觉。结果：采用配对t检验分析比率数据，采用配对Wilcoxon检验分析有序数据。帕金森病患者在动觉测试中的表现明显差于对照组（P= 0.001）。醚subtests.Conclusions：没有视觉指导，帕金森病患者有更大的困难，在感知的程度上的一个目标远离身体，一个任务，需要依赖本体感觉反馈的运动。当帕金森病患者能够使用触觉时，他们在对身体表面的目标进行运动时并不比对照组更困难。帕金森病患者的运动困难可能部分与本体感觉下降有关。增强动觉意识的活动可能是治疗这些患者的重要辅助手段。
Objective: To determine whether there is a complex sensory disturbance that may be contributing to the motor deficit in patients with Parkinson disease.Design: Comparison of performance by patients and healthy, age- and sex-matched subjects in tests of various sensory functions.Setting: The Center for Human Performance and Testing at a university hospital and research center.Participants: Ten subjects with Parkinson disease and 10 control subjects matched for age and sex.Main Outcome Measure: Performance on 4 subtests of the Sensory Integration and Praxis Test: finger identification, graphesthesia, localization of tactile stimuli,and kinesthesia.Results: Data were analyzed using paired t tests for ratio data and the paired Wilcoxon test for ordinal data. Patients with Parkinson disease performed significantly worse (P=.001) than the control patients on the test of kinesthesia. There were no significant differences between the 2 groups on the ether subtests.Conclusions: Without visual guidance, patients with Parkinson disease had more difficulty in perceiving the extent of a movement made to a target away from the body, a task requiring reliance on proprioceptive feedback. Parkinsonian patients had no more difficulty than controls in making movements to a target on the surface of the body when they could use tactile sensations. Movement difficulties inpatients with Parkinson disease may relate in part to a decrease in proprioception. Activities that enhance kinesthetic awareness may be an important adjunct to the treatment of these patients.