Radiation recall -: Another call with tamoxifen
Radiation recall -: Another call with tamoxifen
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DOI：
10.1080/028418699432653
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发表时间：
1999-01-01
期刊：
影响因子：
3.1
通讯作者：
Bergh, J
中科院分区：
文献类型：
--
作者：
Boström, Å;Sjölin-Forsberg, G;Bergh, J
他莫昔芬一种非甾体抗雌激素，已被用作雌激素受体阳性乳腺癌患者的辅助治疗超过10年。这种疗法很少发现皮肤的皮肤不良副作用。在这项研究中，我们提出了20例不良皮肤反应与他莫昔芬在1979年至1997年报告的瑞典药物不良反应登记册和1160皮肤副作用报告，他世界卫生组织的国际合作计划石油药物监测。本文还详细讨论了一个新的病例报告，放射回忆与他莫昔芬，没有迹象表明，尽管18个月的治疗与他莫昔芬类似托瑞米芬重新激活。这个病例说明托瑞米芬可以作为接受过放射治疗的患者的二线治疗。
Tamoxifen. a nonsteroidal antioestrogen, has been used as an adjuvant therapy in patients with oestrogen-receptor positive breast cancer for more than 10 years. Few cutaneous adverse side-effects of the skin are found with this therapy. In this study we present 20 cases of adverse skin effects in relation to tamoxifen during 1979-1997 reported to the Swedish Adverse Drugs Reaction Register and 1160 skin side-effects reported to he World Health Organisation's International Collaborative Programme oil Drug Monitoring. One new case report of radiation recall in conjunction to tamoxifen, with no sign of reactivation despite 18 months treatment with the tamoxifen analogue toremifene is also discussed in detail. This case illustrates that toremifene can be used as a second-line therapy in patients who have received radiation recall, on tamoxifen.