Peptoid transporters: effects of cationic, amphipathic structure on their cellular uptake

Peptoid transporters: effects of cationic, amphipathic structure on their cellular uptake
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DOI:
10.1039/c2mb25197c
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发表时间:
2012-01-01
影响因子:
--
通讯作者:
Barron, Annelise E.
Barron, Annelise E.
中科院分区:
生物3区
文献类型:
--
作者:
Huang, Wei;Seo, Jiwon;Barron, Annelise E.

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两个阳离子,两亲性类肽(聚-N-取代的甘氨酸)被开发为新的分子转运蛋白,具有广泛的细胞摄取,并利用不同的内化机制,从纯阳离子聚胍比较。
Two cationic, amphipathic peptoids (poly-N-substituted glycines) were developed as new molecular transporters, which have extensive cellullar uptake and utilize different internalization mechanisms from purely cationic polyguanidine comparators.