RECRUITMENT OF MEN WHO HAVE SEX WITH MEN FOR LARGE HIV INTERVENTION TRIALS: ANALYSIS OF THE EXPLORE STUDY RECRUITMENT EFFORT

RECRUITMENT OF MEN WHO HAVE SEX WITH MEN FOR LARGE HIV INTERVENTION TRIALS: ANALYSIS OF THE EXPLORE STUDY RECRUITMENT EFFORT
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DOI:
10.1521/aeap.2010.22.1.28
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发表时间:
2010-02-01
影响因子:
1.8
通讯作者:
Koblin, Beryl
Koblin, Beryl
中科院分区:
医学4区
文献类型:
--
作者:
Barresi, Patrick;Husnik, Marla;Koblin, Beryl

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测试艾滋病毒预防策略需要研究人员招募艾滋病毒感染高风险的参与者。来自EXPLORE研究的数据,一项涉及男男性行为者(MSM)的行为干预试验,被用来研究招募策略与参与者特征、性风险行为和艾滋病发病率之间的关系。EXPLORE研究使用了各种各样的招募策略;没有一种策略占注册男性的20%以上。年轻男性和有色人种更有可能通过俱乐部和酒吧外展、朋友推荐和街头外展被招募。报告有10个或更多性伴侣的男性更有可能通过广告和街头宣传被招募。报告无保护性行为的男性更有可能通过诊所转诊被招募。艾滋病毒感染率没有显着差异的招聘策略。我们的研究结果支持需要一个广泛的招募策略,以吸引高风险的艾滋病毒进入临床研究的男男性接触者。
Testing HIV prevention strategies requires that researchers recruit participants at high risk of HIV infection. Data from the EXPLORE Study, a behavioral intervention trial involving men who have sex with men (MSM), were used to examine the relationship between recruitment strategies and participant characteristics, sexual risk behaviors and HIV incidence. The EXPLORE Study used a wide variety of recruitment strategies; no one strategy accounted for more than 20% of enrolled men. Younger men and men of color were more likely to be recruited through club and bar outreach, friend referral, and street out-reach. Men reporting 10 or more sexual partners were more likely to be recruited through advertising and street outreach. Men reporting unprotected sex were more likely to be recruited through clinic referrals. HIV incidence did not significantly differ by recruitment strategy. Our findings support the need for a wide range of recruitment strategies in attracting MSM at high risk for HIV into clinical studies.