Injectable scaffolds: Preparation and application in dental and craniofacial regeneration.
Injectable scaffolds: Preparation and application in dental and craniofacial regeneration.
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DOI：
10.1016/j.mser.2016.11.001
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发表时间：
2017-01
期刊：
影响因子：
--
通讯作者：
Liu X
中科院分区：
文献类型：
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作者：
Chang B;Ahuja N;Ma C;Liu X
可注射支架对于组织再生是有吸引力的，因为它们提供了比预成型支架更多的优点。本文提供了一个全面的审查，目前正在研究的可注射支架的牙齿和颅面组织再生。首先，我们提供了一个可注射支架材料的概述，包括天然的，合成的和复合的生物材料。接下来，我们讨论了各种特征参数和凝胶化机制的可注射支架。先进的可注射支架系统，近年来开发的说明。此外，我们还总结了可注射支架在牙髓、牙本质、牙周膜、颞下颌关节和牙槽骨等牙颌面组织再生中的应用。最后，我们对牙科和颅面组织再生的可注射支架的观点提供了这一领域的未来发展的路标。
Injectable scaffolds are appealing for tissue regeneration because they offer many advantages over pre-formed scaffolds. This article provides a comprehensive review of the injectable scaffolds currently being investigated for dental and craniofacial tissue regeneration. First, we provide an overview of injectable scaffolding materials, including natural, synthetic, and composite biomaterials. Next, we discuss a variety of characteristic parameters and gelation mechanisms of the injectable scaffolds. The advanced injectable scaffolding systems developed in recent years are then illustrated. Furthermore, we summarize the applications of the injectable scaffolds for the regeneration of dental and craniofacial tissues that include pulp, dentin, periodontal ligament, temporomandibular joint, and alveolar bone. Finally, our perspectives on the injectable scaffolds for dental and craniofacial tissue regeneration are offered as signposts for the future advancement of this field.