Measurement of circumferential tumor extent of colorectal cancer on CT colonography: relation to clinicopathological features and patient prognosis after surgery
Measurement of circumferential tumor extent of colorectal cancer on CT colonography: relation to clinicopathological features and patient prognosis after surgery
复制标题
DOI：
10.1007/s11604-021-01141-5
复制
发表时间：
2021-05
影响因子：
2.1
通讯作者：
Daisuke Tsurumaru;N. Takatsu;Satohiro Kai;E. Oki;K. Ishigami
中科院分区：
文献类型：
--
作者：
Daisuke Tsurumaru;N. Takatsu;Satohiro Kai;E. Oki;K. Ishigami
目的探讨结直肠癌周围型肿瘤CT结肠成像(CTC)范围与临床病理特征(包括术后预后)的关系。材料与方法本研究于2013年1月至2019年12月在本院进行，共纳入195例结直肠癌患者，其中男性110例，女性85例，平均年龄64.7岁。结果肿瘤周围率与肿瘤侵袭深度(T)、淋巴结转移(N)、远处转移(M)及分期有关。Kruskal-Wallis检验显示T、N和分期有显著差异(p<； 0.0001，p= 0.0021和p<； 0.0001)，Wilcoxon秩和检验显示M有显著差异(p= 0.0015)。经LOG-RANK检验，高CER组与低CER组的OS和DFS差异无统计学意义。结论周围肿瘤范围与结直肠癌的TNM分期和分期有关，与患者术后预后无关。
PurposeTo examine the relationship between circumferential tumor extent of colorectal cancer (CRC) on CT colonography (CTC) and clinicopathological features including patient prognosis after surgery.Materials and methodsThis retrospective study performed at our institution from January 2013 to December 2019 enrolled 195 consecutive patients (110 men, 85 women; mean age, 64.7 years) with CRC evaluated by contrast-enhanced CTC before surgery. The circumferential tumor extent rate (CER) was measured by CTC in virtual colon dissection (VCD) mode to examine the relation between the CER and clinicopathological features and patient prognosis.ResultsCER had association with tumor invasion depth (T), nodal involvement (N), distant metastasis (M), and stage. The Kruskal–Wallis tests showed significant difference for T, N and the stage (p< 0.0001,p= 0.0021 andp< 0.0001) and Wilcoxon rank sum test showed significant difference for M (p= 0.0015). According to the log-rank test, there were no significant differences in OS or DFS between patients with high and low CER.ConclusionCircumferential tumor extent was significantly correlated with TNM categories and stage of CRC, but not with patient prognosis after surgery.