Clinical significance of microembolus detection by transcranial Doppler sonography in cardiovascular clinical conditions.
Clinical significance of microembolus detection by transcranial Doppler sonography in cardiovascular clinical conditions.
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DOI：
10.1016/j.ijsu.2005.12.001
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发表时间：
2006-01-01
期刊：
影响因子：
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通讯作者：
Hudorovic, Narcis
中科院分区：
文献类型：
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作者：
Hudorovic, Narcis
经颅多普勒可以检测到微栓子信号，其特点是单向高强度增加、持续时间短、随机发生，产生“呼啸”声。微栓塞信号已被证明代表血流中的固体或气体颗粒。在许多临床心血管环境中都检测到了微栓子：颈动脉狭窄、主动脉弓斑块、心房颤动、心肌梗死、人工心脏瓣膜、卵圆孔未闭、瓣膜狭窄、侵入性手术（血管造影、经皮腔内血管成形术）和手术（颈动脉、体外循环）期间。尽管迄今为止进行了大量研究，但微栓塞信号的临床意义仍不清楚。本文概述了微栓子检测技术和临床方面的发展和现状。
Transcranial Doppler can detect microembolic signals, which are characterized by unidirectional high intensity increase, short duration, and random occurrence, producing a "whistling" sound. Microembolic signals have been proven to represent solid or gaseous particles within the blood flow. Microemboli have been detected in a number of clinical cardiovascular settings: carotid artery stenosis, aortic arch plaques, atrial fibrillation, myocardial infarction, prosthetic heart valves, patent foramen ovale, valvular stenosis, during invasive procedures (angiography, percutaneous transluminal angioplasty) and surgery (carotid, cardiopulmonary bypass). Despite numerous studies performed so far, clinical significance of microembolic signals is still unclear. This article provides an overview of the development and current state of technical and clinical aspects of microembolus detection.