On-line parameter identification of systemic circulation using the delta operator.
On-line parameter identification of systemic circulation using the delta operator.
复制标题
使用 delta 算子在线识别体循环参数。
DOI：
10.1046/j.1525-1594.2002.06931_5.x
复制
发表时间：
2002
影响因子：
2.4
通讯作者：
T. Tsutsui
中科院分区：
文献类型：
--
作者：
R. Kosaka;Y. Sankai;T. Jikuya;T. Yamane;T. Tsutsui
为了发展有效的医疗保健与人工心脏，我们提出了一种新的方法，在线参数识别的体循环使用delta算子，可以计算时变的和不可测的血液动力学的内部人体的一些测量数据：主动脉压力和总流量在真实的时间。该方法包括：第一，配置有生理参数Ca（主动脉顺应性）和Rp（总外周阻力）的动态生理模型;第二，使用delta算子的系统识别方法。在计算机仿真研究中，我们可以确认识别生理参数的有效性。在左心室辅助系统的动物实验中，可以在线识别生理参数Ca = 1.8（ml/mm Hg）和Rp = 0.8（mm Hg s/ml）。
To develop effective medical care with the artificial heart, we propose a new method, on-line parameter identification of the systemic circulation using the delta operator which can calculate the time-varying and unmeasured hemodynamics of the internal human body from some measured data: aortic pressure and total flow in real time. This method consists of first, a dynamic physiological model which is configured with the physiological parameters Ca (aortic compliance) and Rp (total peripheral resistance); and second, a system identification method using the delta operator. In the computer simulation study, we could confirm the effectiveness to identify the physiological parameters. In animal experiments with a left ventricular assist system, the physiological parameters, Ca = 1.8 (ml/mm Hg) and Rp = 0.8 (mm Hg s/ml), could be identified on-line.